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. 2020 Jun;70(3):205–215. doi: 10.30802/AALAS-CM-19-000049

Figure 1.

Figure 1.

Design for conditional expression of human IL8 in mice. Human IL8 cDNA was inserted into the pCALL2 plasmid polylinker region to generate IL8-transgenic mice that encode Cre-inducible IL8. IL8-transgenic mice were then bred with GDF5-Cre mice with inducible Cre activity in synovial joints and intervertebral discs.