Table 2.

The central nervous system manifestation of the emerging corona viruses (SARS/MERS).

Case	Author/Year	Age/sex	Neurological Diagnosis	Supportive lab results	Imaging	Comorbidities	Status
1.	Hung, 2003	45/F	Status epilepticus	Serum+VE/CSF +VE SARS-CoV	CT: Normal	RND, fungal peritonitis	A
2.	Lau, 2004	32/F	Generalized seizure	Serum+VE/CSF +VE SARS-CoV	Normal MRI, EEG	Pregnancy	A
3.	Umapathi, 2004	68/F	LVCI	Serum+VE SARS-CoV	Brain CT: Infarction	no vascular risk factors	A
4		64/F	LVCI	Serum+VE SARS-CoV	Brain CT: MCA infarction	no stroke risk factors	D
5		54/F	LVCI	Serum+VE/SARS-CoV	Brain CT PCA and MCA	Dyslipidaemia and hyperthyroidism	D
6		63/M	LVCI	Serum+VE/CSF −VE SARS-CoV	Brain CT: infarction	DM, HTN, IHD	A
7		39/M	Right occipital lobe Infartion (Autopsy)	Serum+VE/CSF −VE SARS-CoV	–	no stroke risk factors	D
8	Arabi, 2015	74/M	Acute disseminated encephalomyelitis	Serum+VE/CSF −VE MERS-CoV ↑protein	MRI T2/FLAIR: hyperdense lesions	DM, HTN and dyslipidemia	D
9		57/M	Vasculopathy	Serum+VE MERS-CoV CSF -No	CT: patchy hypodense lesions	DM, HTN	D
10		45/M	Encephalitis	Serum+VE/CSF −VE MERS-CoV ↑protein	MRI T2/FLAIR: hyperdense lesions	DM, HTN, PAD	A
11	Al-Hameed, 2017	42/F	Spontaneous ICH	Serum+VE MERS-CoV	CT: SAH	RND, DM	D
ABBREVIATION: LVC – large vessel cerebral infarctions, ICH Intracranial Hemorrhage, +VE – Positive, -VE – Negative, CSF – Cerebrospinal fluid, RND – Renal Disease, DM – Diabetes mellitus, HTN – Hypertension, PAD – peripheral artery disease, Hypertension, IHD – Ischemic hart disease, A – Alive, D – Dead