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HCR of all compounds IC50N vs. IC50A.
| Compounds | HT29 | HCT116 | ||||
|---|---|---|---|---|---|---|
| IC50N | IC50A | HCR (IC50N/IC50A) | IC50N | IC50A | HCR (IC50N/IC50A) |
|
| 1b | >500 | 204.5 | >2.44 | 148.6 | 59.36 | 2.50 |
| 2b | >500 | >500 | - | >500 | >500 | - |
| 2c | >500 | >500 | - | >500 | >500 | - |
| 3b | >500 | >500 | - | 267.1 | 97.27 | 2.74 |
| 3c | >500 | >500 | - | >500 | >500 | - |
Abbreviations: IC50: Concentration of an inhibitor where the response is reduced by half; Normoxia (N); Anoxia (A); Hypoxia selectivity cytotoxicity ratio (HCR).
