Figure 1.

Schematic representation of the organization of the five protein subunits composing the major GABA_A complex isoforms. There are two β₃ subunits, one γ₂ subunits and two among six α subunits (where n varies from 1 to 6). The circle in bold corresponds to the chloride channel. The binding sites of the neurotransmitter GABA and of the BzR ligands are evidenced by filled circles and, respectively, a square.