Table 4.
Antifungal activity of the compounds 3, 4, 13, 23, 24, 26, 27, and 31. MIC and MFC are expressed in µg/mL.
|
C. Albicans ATCC 10231 |
A. Fumigatus ATCC 46645 |
T. Rubrum FF5 |
M. Canis FF1 |
E. Floccosum FF9 |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| MIC | MFC | MIC | MFC | MIC | MFC | MIC | MFC | MIC | MFC | |
| 3 | > 128 | > 128 | > 128 | > 128 | 16 | 64 | 16 | 16 | 16 | 64 |
| 4 | > 128 | > 128 | > 128 | > 128 | 128 | > 128 | > 128 | > 128 | > 128 | > 128 |
| 13 | > 128 | > 128 | > 128 | > 128 | 128 | > =128 | > 128 | > 128 | > 128 | > 128 |
| 23 | > 128 | > 128 | > 128 | > 128 | 128 | > 128 | > 128 | > 128 | > 128 | > 128 |
| 24 | 128 | > 128 | > 128 | > 128 | > 128 | > 128 | > 128 | > 128 | > 128 | > 128 |
| 26 | > 128 | > 128 | > 128 | > 128 | 32 | > 128 | 32 | 64 | 32 | > 128 |
| 27 | >=128 | > 128 | > 128 | > 128 | 64 | 64 | 32 | >128 | 64 | > 128 |
| 31 | > 128 | > 128 | > 128 | > 128 | 128 | > 128 | > 128 | > 128 | 128 | > 128 |
MIC, minimum inhibitory concentration; MFC, minimum fungicidal concentration.