Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 13;25(10):2295. doi: 10.3390/molecules25102295

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Crystal structure of the N2-acetylguanine-GR complex. (A) Hydrogen bonding interactions between the ligand and GR. (B) Superimposition of the N2-acetylguanine-GR complex with the guanine-GR complex (grey). The base of nucleotide C74 is stacked between nucleotides 73 and 75 in the guanine-GR complex, whereas in the N2-acetylguanine-GR complex the base of C74 is situated in the major groove adjacent to the base pairs A19-U77 and U20-A76 in the P1 helix. (C) Hydrogen bonding interactions between C74 and two base pairs in the P1 helix.