Table 1.
Characteristics of 34 patients with chronic venous disease (CVD) and 19 non-CVD controls included in the study.
| Characteristic | CVD Population (n = 34) | Control Population (n = 19) | P |
|---|---|---|---|
| Age | 44.12 ± 10.07 1 | 36.58 ± 9.97 1 | 8.387 × 10−3 |
| 27–78 2 | 24–55 2 | ||
| Body Mass Index | 23.85 ± 2.35 1 | 23.12 ± 3.93 1 | 0.117 |
| 20.13–28.76 2 | 19.33–32.6 2 | ||
| Smoking: Current | 5 (14.7%) | 0 (0%) | 1.296 × 10−4 |
| Smoking: Former | 13 (38%) | 0 (0%) | |
| Smoking: Never | 16 (47%) | 19 (100%) | |
| Sex: Male | 17 (50%) | 9 (47%) | 1 |
| Sex: Female | 17 (50%) | 10 (53%) | |
| Signs and symptoms | |||
| Pain | 7 (20.6%) | NA | |
| Ankle-brachial index | 0.96 ± 0.048 1 | NA | |
| 0.71–0.99 2 | |||
| Extended anatomical classification | |||
| Great saphenous vein (above knee) | 23 (67.7%) | NA | |
| Great saphenous vein (below knee) | 7 (20.6%) | NA | |
| Small saphenous vein | 3 (8.8%) | NA | |
| Great and small saphenous vein | 1 (2.9%) | NA | |
| Medication | |||
| Micronized diosmin | 19 (55.9%) | NA | |
| Preparation with vitaminum C, hesperidin and Ruscus aculeatus extract | 10 (29.4%) | NA | |
| Both medications | 5 (14.7%) | NA | |
1 mean ± SD, 2 range. Statistical significance (P) of differences between chronic venous disease (CVD) and control group in age and BMI was calculated using two-sided Mann Whitney U test, and in sex and smoking was calculated using Fisher exact test. Inapplicable data were addressed to “NA”.