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Graphic representation of TTR tetramer. (A) The TTR tetramer composed by four equal monomers assembled by 222 molecular symmetry. The tetramer is crossed by thyroxin binding pockets (T4-BP). (B) The TTR tetramer rotated of 90°. (C) Representation of the dimer composed by two identical monomers. Each monomer is composed by strands D, A, G H, C, B, E and F, and a short EF α-helix.
