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. 2020 May 25;25(10):2453. doi: 10.3390/molecules25102453

Figure 2.

Figure 2

Antiobesity effects of Gentiana lutea (GL) extract on high fat diet (HFD)-induced obese mice. After 12 weeks of experiment, (A) the total fat% and (B) total body weight of mice were measured in normal diet (Sham), HFD (Control (Con)), and HFD mice with the administration of 100 (GL100) or 200 (GL200) mg/kg/day of GL extract. The total fat% and total body weight of all mice were measured using a PIXImus small animal densitometer and an electronic scale, respectively. (C) Hematoxylin and eosin (H&E)-stained adipose cell diameters were individually measured using the CaseViewer program. (D) The number of lipid deposition in H&E-stained liver was calculated in at least five images in each group. * p < 0.05 vs. Con. # p < 0.05 vs. GL100. (Tukey’s honest significant difference post hoc test, analysis of variance). H&E-stained images of the (E) abdominal visceral fat and (F) liver tissues. Six animals in each group were used for this experiment.