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. 2020 May 12;25(10):2281. doi: 10.3390/molecules25102281

Table 11.

List of single nucleotide polymorphisms (SNPs) identified in the TritryDB database, with information regarding the ancestral allele, polymorphic allele, allelic frequency, and amino acid position for each species and enzyme studied. The SNPs with the highest allelic frequencies are highlighted in bold.

DHODH
Species ID TritryDB Non-Synonymous SNP Allele/Amino Acid Allele Frequency Protein Position
L. major LMJSD75 16001070 - - - -
L. braziliensis LbrM.16.0550 A G (Ala)/A (Thr) 0.50/0.50 301
T T (Val)/C (Ala) 0.75/0.25 205
A G (Gly)/A (Ser) 0.50/0.50 6
GPDH
L. major LmjF.10.0510 C G (Arg)/C (Pro) 0.83/0.17 180
L. braziliensis LbrM.10.0640 - - - -
PTR1
L. major LmjF.23.0270 A G (Gly)/A (Glu) 0.60/0.40 25
L. braziliensis LbrM.23.0300 - - - -
TR
L. major LMJLV39 050008400 - - - -
L. braziliensis LbrM.05.0350 T C (Ala)/T (Val) 0.67/0.33 36
G A (Thr)/G (Ala) 0.67/0.33 97
G A (Asp)/G (Gly) 0.67/0.33 112
G A (Asn)/G (Ser) 0.67/0.33 116
C G (Glu)/C (Asp) 0.67/0.33 115
G A (Asn)/G (Ser) 0.67/0.33 116
A C (Gln)/A (Lys) 0.67/0.33 130
A A (Asn)/G (Leu) 0.50/0.50 144
C G (Lys)/C (Asn) 0.67/0.33 480
UGPase
L. major LMJLV39 180015400 - - - -
L. braziliensis LbrM.18.1050 - - - -