Table 12.
Antileishmanial activity of lignans against L. major and L. braziliensis promastigotes.
ID | Name | IC50 (µM) | |
---|---|---|---|
L. major | L. braziliensis | ||
156 | Secoisolariciresinol | - | 9.28 |
158 | Pinoresinol-4-O-β-d-glucopyranoside | >50 | 36.35 |
159 | Epipinoresinol-4-O-β-d-glucopyranoside | 36.51 | 5.39 |
160 | Pinoresinol-4-O-β-d-apiofuranosyl-(1→2)-β-d-glucopyranoside | >50 | 13.77 |
Meglumine antimoniate | >40 | >40 | |
Amphotericin B | 12.4 | 18 |