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. 2020 May 12;25(10):2281. doi: 10.3390/molecules25102281

Table 12.

Antileishmanial activity of lignans against L. major and L. braziliensis promastigotes.

ID Name IC50 (µM)
L. major L. braziliensis
156 Secoisolariciresinol - 9.28
158 Pinoresinol-4-O-β-d-glucopyranoside >50 36.35
159 Epipinoresinol-4-O-β-d-glucopyranoside 36.51 5.39
160 Pinoresinol-4-O-β-d-apiofuranosyl-(1→2)-β-d-glucopyranoside >50 13.77
Meglumine antimoniate >40 >40
Amphotericin B 12.4 18