Table 1.
Blood Product | L-PRF | CGF | APG |
---|---|---|---|
Protocol | 2700 rpm for 12 min | 2400 rpm alternated | 2400 rpm |
to 3000 rpm for 14 min | 10 min | ||
Flow | One step continuous | One step discontinuous | Two step clot activation with CaCl2 |
PDGF levels [27] (ng/mL) | High | Highest | Low |
VEGF levels [27] (pg/mL) | Highest | High | Low |
TGF-β 1 [27] (ng/mL) | High | Highest | Low |
Speed-rate | Fast | Mixed | Fast |
Reproducibility | No bias | No bias | Possible bias |
Use of Anticoagulants | NO | NO | YES |
Fibrin density | High | Medium | Low |
Speed of fibrin formation | High | High | Low |
Fibrin morphology | Tetramolecular | Tetramolecular | Tetramolecular |
Dose | 9 mL | 9 mL | 9 mL |
Handling | Easy | Easy | Complex |
Expense | Low cost | Low cost | High cost |
Young’s modulus [27] | 0.35 Gpa | 70 kpa | 60 kpa |
PDGF: platelet-derived growth factor, VEGF: vascular endothelial growth factor, TGF-β 1: transforming growth factor β 1.