Figure 4.
Effect of EFV and RPV on lipid metabolism. (A) Relevant metabolite changes grouped by chemical classes related to EFV or (B) RPV regimen. Data are expressed as log2 (fold change) and values between 24 and 12 weeks were compared using paired Student’s t-test p-values. *p values < 0.05 were considered significant and φp values >0.05 but <0.10 were considered relevant in the results interpretation. Abbreviations: AC, acyl carnitine; Cer, ceramide; ChoE, cholesteryl ester; DAG, diacylglycerols; LPC, lysophosphatidylcholine; LPI, lysophosphatidylinositol; oxFA, oxidized fatty acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; SM, sphingomyelins; ST, total steroid; TAG, triacylglycerol.