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. 2020 Jun 2;2020:1657896. doi: 10.1155/2020/1657896

Figure 1.

Figure 1

JK184 inhibits the growth of BCa cells. (a) JK184 inhibited BCa cell growth. Cell growth was measured in MCF-7, MDA-MB-231, MDA-MB-468, BT549, SKBR3, and MCF-10A cells treated with the indicated concentrations of JK184 for 24 hours. (b) JK184 inhibited BCa cell proliferation measured by EdU labeling. (c) JK184 suppressed colony formation in BCa cells. Cells (200 cells/well) were cultured in the indicated concentrations of JK184 for 2 days and continuously cultured in a fresh medium for another 12 days. Representative images (left) and survival fraction were shown (right). (d) The status of cells that were treated with JK184 in different concentrations. Scale bar, 50 μm. (e) The number of cells that have a clear cytoplasm (viable cells) was counted after being treated with indicated concentrations of JK184 for 24 hours. ∗, P < 0.05; ∗∗, P < 0.01; ∗∗∗, P < 0.001.