Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
JK184 promotes autophagy flux in BCa cells. (a-b) Cells were transiently transfected with an RFP-GFP tandem fluorescent-tagged LC3 (RFP-GFP-LC3). Furthermore, cells were treated with 4 nm JK184 or in combination with 10 μM chloroquine (CQ) for 24 hours. Scale bar, 10 μm. (c-d) (Above) endogenous LC3 puncta analyzed by immunofluorescence in cells treated as in (a). (Below) total number of endogenous LC3 puncta per cell. ∗∗, P < 0.01; ∗∗∗, P < 0.001. Scale bar, 10 μm.
