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. 2020 Jun 10;14:24. doi: 10.1186/s40246-020-00270-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 6 — Construction of co-expression network and functional analysis. a The co-expression network of differentially expressed (DE) lncRNAs and DEmRNAs. The red color shows the upregulated lncRNAs or mRNAs, and the green color denotes the downregulated lncRNAs or mRNAs. Squares and circles, respectively, represent lncRNAs and mRNAs. b GO and KEGG pathways of DEmRNAs. Horizontal axis and vertical axis represent the gene number and term, respectively; the color and size of the bots indicate the significant P value, and the closer the color is to red, the higher the significance