Table 1.

Tumor‐associated antigen T‐cell responses developed after treatment with the TriAdeno vaccine regimen

Immune responses reported in this table are calculated by comparing the absolute number of CD4⁺ or CD8⁺ T cells producing cytokine (IFN, IL‐2, TNFa) or positive for CD107a per 1 × 10⁶ PBMCs plated at the start of the in vitro stimulation at the specified time points after vaccine. Background (obtained with the negative control peptide pool, human leukocyte antigen [HLA]) and any response prior to vaccine are subtracted: [TAA after vaccine – HLA after vaccine] – [TAA before vaccine – HLA before vaccine]. Positive immune responses are defined as >250 (highlighted).

Abbreviations: IFNg, interferon gamma; IL‐2, interleukin‐2; PT, patient; TNF, tumor necrosis factor.