TABLE 2.

Cognitive Function Neuro-QoL Domain T-Scores for Pediatric Patients With SWS by Extent of Total SWS (the Sum of a Subject’s Brain, Skin, and Eye Involvement Scores), Brain, Skin, and Eye Involvement

Sturge-Weber Extent	Extent of Involvement	n	%	Cog. Fxn. Neuro-QoL (Mean T-score ± S.D.)	R	P-Value
Total SWS involvement	0	0	0.00	N/A	−0.63	0.002
	1	4	19.05	47.35 ± 2.29
	2	5	23.81	45.38 ± 7.07
	3	4	19.05	38.18 ± 6.66
	4	5	23.81	35.86 ± 6.95
	5	3	14.29	36.10 ± 10.45
	6	0	0.00	N/A
Brain involvement	None	0	0.00	N/A	N/A	0.1
	Unilateral	18	81.82	41.76 ± 7.62
	Bilateral	4	18.18	35.48 ± 7.05
Skin involvement	None	4	19.05	47.35 ± 2.29	−0.46	0.04
	Unilateral	11	52.38	40.27 ± 8.09
	Bilateral	6	28.57	37.37 ± 8.22
Eye involvement	None	10	47.62	44.98 ± 6.42	−0.58	0.005
	Unilateral	9	42.86	38.17 ± 6.87
	Bilateral	2	9.52	31.65 ± 9.97

Abbreviations:

Neuro-QoL = quality of life in neurological disorders

SWS = Sturge-Weber syndrome

A higher T-score represents more cognitive function Neuro-QoL, and it is standardized to have a standard deviation of 10 with 50 representing the mean value in the reference population (see text for description). An increased extent of skin, eye, and total SWS involvement correlated with lower cognitive function Neuro-QoL. Extent of brain involvement was not significantly associated with cognitive function Neuro-QoL.