Table 2.
Characteristics of Patients With and Without PC Variation.
| Patient Characteristics | Included Patients (n = 287) | ||
|---|---|---|---|
| Patients: PC Variation, Chromogen PC Activity ≥70% | Patients: PC Variation, Chromogen PC Activity <70% | Patients: Without PC Variation | |
| Number of patients | 20 | 81 | 186 |
| Females | 14 | 47 | 154 |
| Males | 6 | 34 | 32 |
| Age (years) | 40.9 ± 19.2 | 36.8 ± 16.8 | 37.1 ± 15.5 |
| PC activity chromogen (%) | 80.5 ± 11.3 | 50.8 ± 11.2 | 77.3 ± 14.7 |
| PC activity clotting (%) | 55.9 ± 10.2 | 44.0 ± 12.0 | 62.7 ± 15.8 |
| PC antigen (%) | 69.9 ± 14.8 | 48.4 ± 16.2 | 65.3 ± 14.1 |
| PC antigen (mg/L) | 2.4 ± 0.3 | 1.9 ± 0.6 | 2.4 ± 0.3 |
| F VIII activity (%) | 116.3 ± 40.6 | 114.9 ± 37.2 | 135.7 ± 53.8 |
| Lupus anticoagulant (lac screen ratio) | 1.3 ± 0.5 | 1.0 ± 0.3 | 1.0 ± 0.2 |
| Deep vein thrombosis | 7 (35%) | 26 (32%) | 64 (34%) |
| Pulmonary embolism | 3 (15%) | 8 (10%) | 21 (11%) |
| Factor V Leiden | 6 (30%) | 10 (12%) | 44 (24%) |
| Women with pregnancy complications | 2 (10%) | 9 (19%) | 42 (27%) |
Abbreviation: PC, protein C.