Table 1.
Clinical variables | Total | Training dataset | Validate dataset |
---|---|---|---|
Sample size | 300 | 210 | 90 |
Survival status | |||
Dead | 152 | 102 | 50 |
Survived | 148 | 108 | 40 |
Median age (year) | 61.94 | 47.59 | 62.76 |
Sex | |||
Female | 101 | 74 | 27 |
Male | 199 | 136 | 63 |
T stage | |||
2 | 188 | 130 | 58 |
3 | 91 | 67 | 24 |
4 | 21 | 13 | 8 |
N stage | |||
0 | 38 | 28 | 10 |
1 | 131 | 94 | 37 |
2 | 80 | 49 | 31 |
3 | 51 | 39 | 12 |
M stage | |||
0 | 273 | 191 | 82 |
1 | 27 | 19 | 8 |
AJCC stage | |||
I | 30 | 21 | 9 |
II | 97 | 70 | 27 |
III | 96 | 65 | 31 |
IV | 77 | 54 | 23 |
Recurrent status | |||
Yes | 125 | 110 | 53 |
No | 157 | 77 | 29 |
Unknown | 18 | 19 | 8 |
Tumor cite | 4 | ||
Antrum | 155 | 110 | 45 |
Body | 107 | 77 | 30 |
Cardia | 32 | 19 | 13 |
Whole | 6 | 4 | 2 |
WHO classification | |||
W/D and M/D tubular | 114 | 89 | 25 |
P/D tubular | 116 | 73 | 43 |
Signet ring cell | 37 | 25 | 12 |
Mucinous | 8 | 5 | 3 |
Papillary | 9 | 6 | 3 |
Other | 16 | 12 | 4 |
Lauren type | |||
Intestinal | 150 | 110 | 40 |
Diffuse | 142 | 95 | 47 |
Mixed | 8 | 5 | 3 |
Molecular subtype | |||
MSS/TP53− | 107 | 79 | 28 |
MSS/TP53+ | 79 | 53 | 26 |
MSI | 68 | 44 | 24 |
MSS/EMT | 46 | 34 | 12 |
EBV status | |||
Positive | 18 | 181 | 76 |
Negative | 257 | 13 | 5 |
Missing | 12 | 16 | 9 |
Adjuvant CCRT | |||
Completed | 73 | 46 | 27 |
Not completed | 7 | 5 | 2 |
Not done | 220 | 129 | 61 |
OP type | |||
TG | 135 | 94 | 41 |
STG | 165 | 116 | 49 |
GC – gastric cancer; AJCC – American Joint Committee on Cancer; WHO – World Health Organization; W/D – well-differentiated; M/D – moderately differentiated; P/D – poorly differentiated; MSS – microsatellite stable; TP53− – tumor protein 53 inactive; TP53+ – tumor protein 53 active; MSI – microsatellite instability; EMT – epithelial-mesenchymal transition; TG – total gastrectomy; STG – subtotal gastrectomy.