Table 1.
Baseline | Occlusion | Reperfusion | ||
---|---|---|---|---|
1 h | 2 h | |||
HR (min−1) | ||||
CON | 357±53 | 332±35 | 347±35 | 351±47 |
SWOP | 367±44 | 341±53 | 341±46 | 353±42 |
CC | 363±49 | 338±45 | 357±37 | 352±49 |
CC+SWOP | 371±55 | 335±51 | 347±43 | 355±45 |
DMSO | 361±47 | 344±42 | 352±45 | 352±30 |
MAP (mmHg) | ||||
CON | 113±12 | 112±14 | 81±12* | 78±12* |
SWOP | 112±10 | 115±13 | 77±13* | 65±12* |
CC | 105±13 | 121±11 | 76±13* | 68±14* |
CC+SWOP | 103±9 | 108±7 | 78±9* | 69±10* |
DMSO | 115±12 | 118±15 | 76±13* | 64±18* |
RPP (min−1·mmHg·103) | ||||
CON | 43±5 | 44±12 | 36±4* | 37±5* |
SWOP | 44±7 | 45±7 | 38±4* | 38±8* |
CC | 44±6 | 44±5 | 36±7* | 35±4* |
CC+SWOP | 47±3 | 48±5 | 37±3* | 36±7* |
DMSO | 46±10 | 48±7 | 36±8* | 33±4* |
Values are presented as mean±SD. The hemodynamics in the 5 experimental groups at baseline, during occlusion, and at reperfusion showed no between-group differences. HR – heart rate; MAP – mean arterial blood pressure; RPP – rate-pressure product; CON – ischemia and reperfusion; SWOP – the second window of protection with sevoflurane; CC – compound C; DMSO – dimethylsulfoxide;
P<0.05 versus baseline.