Table 3.
Univariate Analysis of Risk Factors for Ischemic Complications after Mastectomy with Immediate Breast Reconstruction Including the Mastectomy Flap Ischemia Risk Score
Variable | Total Mastectomies (N) | Mastectomies with Ischemic Complication (%) | Unadjusted OR (95% CI) | P |
---|---|---|---|---|
No. | 45 | – | – | |
Age | ||||
<50 y | 24 | 7 (29.2%) | 1.8214 (0.5305–6.2540) | 0.3407 |
≥50 y | 21 | 9 (42.9%) | ||
BMI | ||||
<30 kg/m2 | 29 | 8 (27.6%) | 2.6250 (0.7341–9.3864) | 0.1377 |
≥30 kg/m2 | 16 | 8 (50.0%) | ||
Current smoking | ||||
Yes | 2 | 1 (50.0%) | 1.8667 (0.1089–32.0108) | 0.6669 |
No | 43 | 15 (34.9%) | ||
Therapeutic indication | ||||
Yes | 28 | 12 (42.9%) | 2.4375 (0.6334–9.3803) | 0.1950 |
No | 17 | 4 (23.5%) | ||
Sentinel lymph node biopsy performed | ||||
Yes | 19 | 10 (52.6%) | 3.7037 (1.0278–13.3467) | 0.0453 |
No | 26 | 6 (23.1%) | ||
Axillary lymph node dissection performed | ||||
Yes | 7 | 1 (14.3%) | 0.2556 (0.0279–2.3406) | 0.2273 |
No | 38 | 15 (39.5%) | ||
Prior radiation | ||||
Yes | 6 | 3 (50.0%) | 2.0000 (0.3534–11.3186) | 0.4332 |
No | 39 | 13 (33.3%) | ||
Prior chemotherapy | ||||
Yes | 18 | 6 (33.3%) | 0.8500 (0.2427–2.9763) | 0.7994 |
No | 27 | 10 (37.0%) | ||
Adjuvant radiation | ||||
Yes | 7 | 2 (28.6%) | 0.6857 (0.1171–4.0151) | 0.6756 |
No | 38 | 14 (36.8%) | ||
Adjuvant chemotherapy | ||||
Yes | 6 | 0 (0.0%) | 0.1096 (0.0058–2.0819) | 0.1410 |
No | 39 | 16 (41.0%) | ||
Nipple-sparing mastectomy | ||||
Yes | 3 | 0 (0.0%) | 0.2294 (0.0111–4.7313) | 0.3404 |
No | 42 | 16 (38.1%) | ||
Implant-based reconstruction | ||||
Yes | 29 | 11 (37.9%) | 1.3444 (0.3678–4.9146) | 0.6545 |
No | 16 | 5 (31.3%) | ||
Acellular dermal matrix | ||||
Yes | 20 | 7 (35.0%) | 0.6731 (0.1353–3.3474) | 0.6286 |
No | 9 | 4 (44.4%) | ||
Sternal notch–nipple distance ≥25 cm | ||||
Yes | 13 | 7 (53.8%) | 2.1875 (0.5462–8.7612) | 0.2689 |
No | 23 | 8 (34.8%) | ||
Nipple–inframammary fold distance ≥10 cm | ||||
Yes | 15 | 6 (40.0%) | 0.8889 (0.2312–3.4181) | 0.8639 |
No | 21 | 9 (42.9%) | ||
Mastectomy flap ischemia risk score >5 | ||||
Yes | 9 | 5 (55.6%) | 2.8409 (0.6378–12.6541) | 0.1707 |
No | 36 | 11 (30.6%) | ||
Mastectomy flap ischemia risk score >6 | ||||
Yes | 6 | 4 (66.7%) | 4.5000 (0.7229–28.0120) | 0.1069 |
No | 39 | 12 (30.8%) | ||
Mastectomy flap ischemia risk score >7 | ||||
Yes | 4 | 3 (75.0%) | 6.4615 (0.6120–68.2200) | 0.1207 |
No | 41 | 13 (31.7%) |
Bold text indicates a significant P value.
BMI, body mass index.