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. 2020 May 18;12(10):9224–9239. doi: 10.18632/aging.103195

Figure 7.

Figure 7

Schematic diagram summarizes the mechanism whereby APLN promotes IL-1β production in OASFs. APLN induces inflammatory IL-1β production in OASFs by downregulating miR-144-3p through the PI3K and ERK signaling pathways.