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. 2020 May 19;12(10):9292–9310. doi: 10.18632/aging.103206

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Copyright © 2020 Chang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Validation of target genes of piRNA-13643 and piRNA-21238. (A) Result of hierarchical clustering for differential genes in thyroid cancer and noncancerous tissue was calculated by TCGA database. (B) Result of volcano for differential genes in thyroid cancer and noncancerous tissue was calculated by TCGA database. (C) Result of hierarchical clustering for differential genes in thyroid cancer with or without metastasis tissue was calculated by TCGA database. (D) Result of volcano for differential genes in thyroid cancer with or without metastasis tissue was calculated by TCGA database. (E) piRNA-13643 target genes prediction using differential genes in thyroid cancer and noncancerous tissue in TCGA database. (F) piRNA-21238 target genes prediction using differential genes in thyroid cancer and noncancerous tissue in TCGA database. (G) piRNA-13643 target prediction using differential genes in thyroid cancer with or without metastasis tissue in TCGA database. (H) piRNA-21238 target prediction using differential genes in thyroid cancer with or without metastasis tissue in TCGA database. (I) Gene Ontology (GO) analysis of piRNA-13643 associated with biological process, molecular function and cellular component. (J) Top twenty signal pathways of piRNA-13643 by KEGG.