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Significantly related genes and hallmarks pathways in ccRCC obtained by GSEA. GSEA was used to perform hallmark analysis for TIMP1 (A–C). The most significant pathways included epithelial-mesenchymal-transition, inflammatory-response, and IL6/JAK/STAT3 signaling. (D) Transcriptional expression profiles of the 100 most significant genes expressed as a heat map.
