TABLE 1.

Participant Characteristics and Samples Available for Each Assay

Characteristic	Control, n = 7				Sleep-Deprived, n = 7				Drug, n = 6
Age, yr
Mean	47.6				48.1				51
SD	9.2				10				9.8
Sex, M/F	2/5				3/4				3/3
Race, C/AA	3/4				3/4				2/4
Samples Available for Each Assay
Participant	Control				Sleep-Deprived				Drug
	Aβ	Tau/p-tau	α-synuclein	pS129-α-synuclein	Aβ	Tau/p-tau	α-synuclein	pS129-α-synuclein	Aβ	Tau/p-tau	α-synuclein	pS129-α-synuclein
1	X	X	X	BLD	X	X	X	BLD	X	X	X	BLD
2	X	X	X	BLD	X	X	X	BLD	X	X	X	BLD
3	X	X	X	X	X	X	X	X	X	X	X	X
4	X	X	X	BLD	X	X	X	BLD	X	X	X	BLD
5	X	X	—	—	X	X	—	—	—	—	—	—
6	X	X	X	BLD	X	X	—	—	—	—	—	—
7	X	X	X	X	—	—	—	—	X	X	X	X
8	—	—	—	—	X	X	X	X	X	X	X	X

AA = African American; Aβ = amyloid-β; BLD = below detection limit; C = Caucasian; F = female; M = male; p-tau = phosphorylated tau;