Table 1.
Complex I subunits in different model organisms
| Homo sapiens | Bos taurus | Yarrowia lipolytica | Drosophila melanogaster | Escherichia coli |
|---|---|---|---|---|
| Core subunits | ||||
| MT-ND1 | MT-ND1 | NU1M | CG34092 | NuoH |
| MT-ND2 | MT-ND2 | NU2M | CG34063 | NuoN |
| MT-ND3 | MT-ND3 | NU3M | CG34076 | NuoA |
| MT-ND4 | MT-ND4 | NU4M | CG34085 | NuoM |
| MT-ND4L | MT-ND4L | NULM | CG34086 | NuoK |
| MT-ND5 | MT-ND5 | NU5M | CG34083 | NuoL |
| MT-ND6 | MT-ND6 | NU6M | CG34089 | NuoJ |
| NDUFS1 | 75 kDa | NUAM | CG2286 | NuoG |
| NDUFS2 | 49 kDa | NUCM | CG1970, CG11913a | NuoD |
| NDUFS3 | 30 kDa | NUGM | CG12079 | NuoC |
| NDUFS7 | PSST | NUKM | CG9172, CG2014a | NuoB |
| NDUFS8 | TYKY | NUIM | CG3944 | NuoI |
| NDUFV1 | 51 kDa | NUBM | CG9140, CG11423a, CG8102a | NuoF |
| NDUFV2 | 24 kDa | NUHM | CG5703, CG6485a | NuoE |
| Accessory subunits | ||||
| NDUFS4 | AQDQ/18 kDa | NUYM | CG12203 | |
| NDUFS5 | PFFD/15 kDa | NIPM | CG11455 | |
| NDUFS6 | 13 kDa | NUMM | CG8680 | |
| NDUFV3 | 10 kDa | CG11752 | ||
| NDUFC1 | KFYI | |||
| NDUFC2 | B14.5b | CG12400 | ||
| NDUFA1 | MWFE | NIMM | CG34439 | |
| NDUFA2 | B8 | NI8M | CG15434 | |
| NDUFA3 | B9 | NI9M | ||
| NDUFA5 | B13 | NUFM | CG6463 | |
| NDUFA6 | B14 | NB4M | CG7712 | |
| NDUFA7 | B14.5a | NUZM | CG3621, CG6914a | |
| NDUFA8 | PGIV | NUPM | CG3683 | |
| NDUFA9 | 39 kDa | NUEM | CG6020 | |
| NDUFA10 | 42 kDa | CG6343 | ||
| NDUFA11 | B14.7 | NUJM | CG9350 | |
| NDUFA12 | B17.2 | N7BM | CG3214 | |
| NDUFA13 | B16.6 | NB6M | CG3446 | |
| NDUFAB1 | SDAPα, SDAPβ | ACPM1, ACPM2 | CG9160 | |
| NDUFB1 | MNLL | CG18624 | ||
| NDUFB2 | AGGG | CG40002, CG40472a | ||
| NDUFB3 | B12 | NB2M | CG10320 | |
| NDUFB4 | B15 | NB5M | CG12859 | |
| NDUFB5 | SGDH | CG9762 | ||
| NDUFB6 | B17 | CG13240 | ||
| NDUFB7 | B18 | NB8M | CG5548 | |
| NDUFB8 | ASHI | NIAM | CG3192 | |
| NDUFB9 | B22 | NI2M | CG9306 | |
| NDUFB10 | PDSW | NIDM | CG8844 | |
| NDUFB11 | ESSS | NESM | CG6008 | |
| NUXM | ||||
| NEBM | ||||
| NUNM | ||||
| NUUM | ||||
| ST1 | ||||
aThe various paralogs for a specific CI subunit. Where multiple paralogs were obtained, the paralog with the most extensive sequence similarity with the human ortholog was listed first in the table