Table 2.

Tissue and Vascular Parameters Used in Simulations

Parameter	Unit	Description (# References)	Value
Lp	m Pa−1 s−1	Vessel permeability (1, 23)	2 × 10−11 (tumor) 3 × 10−12 (normal)
LpLSL/V	Pa−1 s−1	Lymphatic filtration coefficient (23)	1 × 10−7
K	m2 Pa−1 s−1	Hydraulic conductivity (23)	1.9 × 10−12 (tumor) 3.8 × 10−13 (normal)
S/V	m−1	Microvascular surface area per unit volume (1, 47)	2 × 104 (tumor) 7 × 103 (normal)
pV	Pa	Microvascular pressure (59)	2,300
πi	Pa	Osmotic pressure in interstitial space (1, 46, 47)	3,230 (tumor) 1,330 (normal)
πV	Pa	Osmotic pressure in microvasculature (46)	2,670
σT	Unitless	Average osmotic reflection coefficient for plasma (1, 50)	0.82 (tumor) 0.91 (normal)