Table 2.

AUCs from Logistic Regression in the First Cohort of 735 Patients Using Percent Change in Mean cBPE as a Predictor for pCR

Patient Cohort	N	pCR Rate (%)	Method	%ΔBPE0_1		%ΔBPE0_2
				AUC	P-Value	AUC	P-Value
Full Cohort	735	35.1	Full stack	0.53	.09*	0.52	.14
			Half stack	0.52	.23	0.52	.18
			Center 5	0.51	.30	0.50	.50
HR+/HER2+	112	33.9	Full stack	0.58	.08*	0.53	.30
			Half stack	0.56	.14	0.53	.31
			Center 5	0.56	.15	0.52	.39
HR+/HER2−	299	19.1	Full stack	0.53	.23	0.61	.01**
			Half stack	0.52	.32	0.60	.01**
			Center 5	0.53	.24	0.59	.02**
HR−/HER2+	61	68.9	Full stack	0.57	.20	0.62	.08*
			Half stack	0.59	.14	0.60	.11
			Center 5	0.56	.25	0.53	.35
HR−/HER2−	263	46.0	Full stack	0.52	.33	0.50	.49
			Half stack	0.51	.42	0.50	.46
			Center 5	0.52	.28	0.54	.15

All measurements were obtained from bias corrected images with poor, adequate, and good segmentation quality. *P < .10; **P < .05.