Table 3.

AUCs from Logistic Regression in the Second Quality Restricted Cohort of 340 Patients Using Percent Change in Mean cBPE as a Predictor for pCR

Patient Cohort	N	pCR Rate (%)	Method	%ΔBPE0_1		%ΔBPE0_2
				AUC	P-Value	AUC	P-Value
Full Cohort	340	33.2	Full stack	0.51	.40	0.55	.08*
			Half stack	0.51	.35	0.54	.11
			Center 5	0.50	.49	0.50	.46
HR+/HER2+	57	31.6	Full stack	0.44	.25	0.51	.44
			Half stack	0.45	.26	0.50	.48
			Center 5	0.57	.21	0.49	.46
HR+/HER2−	140	17.9	Full stack	0.54	.25	0.61	.05**
			Half stack	0.53	.33	0.59	.07*
			Center 5	0.57	.13	0.59	.08*
HR−/HER2+	27	81.5	Full stack	0.78	.03**	0.66	.14
			Half stack	0.87	.01**	0.65	.15
			Center 5	0.78	.03**	0.64	.18
HR−/HER2−	116	41.4	Full stack	0.53	.32	0.58	.08*
			Half stack	0.55	.17	0.57	.09*
			Center 5	0.50	.47	0.50	.47

All measurements were obtained from bias-corrected images with adequate and good segmentation quality only. *P < .10; **P < .05.