Table. 2.
Selected results of DAVID functional annotation clustering for differentially expressed genes in the GE of the PD 10 and DOPP 2.5 and 3.5 mouse uteri.
| Representative functional terms of overrepresented annotation clustersa | Enrichment scoreb |
|---|---|
| PD 10 | |
| Morphogenesis of a branching structure (10, 9.8) | 6.0 |
| Lung development (6, 6.6); respiratory tube development (6, 6.5) | 3.2 |
| EGF-like calcium-binding (6, 8.9) | 3.1 |
| Isoprenoid metabolic process (6, 15.3); retinoid metabolic process (5, 21.8) | 2.7 |
| Concanavalin A-like lectin/glucanase, subgroup (5, 8.9) | 2.4 |
| Glycosaminoglycan binding (6, 6.3); carbohydrate binding (7, 2.6) | 2.2 |
| Mesenchymal cell differentiation (4, 9.9) | 1.9 |
| Branching involved in ureteric bud morphogenesis (3, 13.0) | 1.6 |
| Cell migration | 1.2 |
| DOPP 2.5 | |
| Cell cycle (26, 2.5) | 5.1 |
| Condensed chromosome (7, 3.5) | 2.5 |
| Retinoic acid metabolic process (4, 14.1); cellular hormone metabolic process (4, 4.7) | 2.0 |
| Collagen (4, 11.4) | 1.9 |
| Alcohol dehydrogenase (3, 18.8) | 1.8 |
| Sulfatase (3, 13.9) | 1.6 |
| NAD(P)-binding domain (6, 2.3) | 1.5 |
| Tight junction (5, 4.9) | 1.4 |
| EGF-like 4; calcium-binding (5, 8.9) | 1.1 |
| DOPP 3.5 | |
| Proteinaceous extracellular matrix (49, 3.4) | 13.9 |
| EGF-like calcium-binding, conserved site (18, 4.6) | 6.0 |
| Polysaccharide binding (20, 3.5) | 5.2 |
| Egf-like domain (26, 2.7) | 4.7 |
| Proteinase inhibitor I1, Kazal (11, 5.6) | 4.5 |
| Regulation of locomotion (14, 3.0) | 2.9 |
| Transmembrane (243, 1.11) | 2.6 |
| Regulation of kinase activity (18, 2.2); regulation of phosphorylation (23, 1.9) | 2.4 |
a
Values within parenthess indicate the number of genes and fold enrichment of the functional term.
b
Geometric mean of member'sP values of the corresponding annotation cluster (in −log10 scale).