Table 3.
The lymphocyte subsets of peripheral blood in of survivors and non-survivors with COVID-19.
| Lymphocyte subset | N | Total | Alive | Died | P value |
|---|---|---|---|---|---|
| CD3+ (%) | 579 | 72 (62–78) | 72 (63–78) | 59 (50–67) | <0.001 |
| CD3 concentration × 10E + 9/L | 246 | 359 (2–901) | 381 (2–918) | 140 (75–190) | 0.023 |
| CD3+CD4+ (%) | 579 | 41 (33–48) | 41 (33–48) | 37 (28–48) | 0.443 |
| CD3+CD4+ concentration × 10E + 9/L | 246 | 200 (1–481) | 227 (1–487) | 71 (46–107) | 0.036 |
| CD3+CD8+ (%) | 579 | 23 (18–30) | 24 (19–30) | 14 (10–18) | <0.001 |
| CD3+CD8+ concentration × 10E + 9/L | 246 | 119 (1–302) | 141 (1–308) | 49 (14–64) | 0.023 |
| NK cell (%) | 415 | 10 (6–17) | 10 (6–17) | 10 (5–12) | 0.29 |
| NK cell concentration × 10E + 9/L | 246 | 76 (0.4–185) | 77 (0.4–188) | 41 (19–102) | 0.453 |
| B lymphocyte (%) | 415 | 13 (9–18) | 12 (9–17) | 16 (10–28) | 0.022 |
| B lymphocyte concentration × 10E + 9/L | 246 | 96 (0.3–178) | 98 (0.3–188) | 55 (22–91) | 0.136 |
| CD4+/CD8+ ratio | |||||
| Max | 577 | 2 (1.4–2.6) | 1.9 (1.4–2.6) | 3.0 (1.9–4.5) | <0.001 |
| Min | 489 | 1.6 (1.2–2) | 1.57 (1.2–2) | 1.6 (1.3–2.3) | 0.336 |
Data are median (IQR), n (%), or n/N (%). Cell count at presentation (cells/ul). p values were calculated by Mann–Whitney U test, χ2 test, or Fisher’s exact test, as appropriate.
NK cell natural killer cell