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. 2020 Jun 11;34(8):2163–2172. doi: 10.1038/s41375-020-0910-1

Table 4.

Clotting factor levels of survivors and non-survivors with COVID-19.

N Total Alive Died P value
PT, s (11–16)
 Baseline 1055 13 (12–13) 13 (12–13) 14 (13–15) <0.001
 Max 1035 13 (12–14) 13 (12–14) 17 (14–20) <0.001
APTT, s (28–43.5)
 Baseline 1055 34 (30–38) 34 (30–37) 35 (300–40) 0.019
 Max 1289 34 (30–38) 34 (30–37) 40 (34–50) <0.001
D-dimer, mg/L (<0.5)
 Baseline 1239 0.4 (0.2–0.9) 0.4 (0.2–0.8) 3.6 (0.9–8) <0.001
 Max 1262 0.6 (0.2–1.6) 0.5 (0.2–1) 8 (6–8) <0.001
Fibrinogen, g/L (2–4)
 Baseline 1304 3.7 (2.9–4.6) 3.6 (2.9–4.5) 4.3 (3.2–5.2) <0.001
 Min 976 3.2 (2.5–3.9) 3.2 (2.6–3.9) 2.6 (1.7–3.9) <0.001

PT prothrombin time, APTT activated partial thromboplastin time.