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. 2020 Jun 9;11(23):2172–2181. doi: 10.18632/oncotarget.27612

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Copyright: © 2020 Corona et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Patients were stratified according to weight loss expressed as percentage of initial weight loss during treatment. The two groups of patients who recorded the highest percentage of weight loss showed a better median PFS and the difference between groups was statistically significant (p < 0.009). (B) Patients were stratified according to the correspondent absolute weight loss expressed in kg. Patients with a weight loss of more than 4.90 kg show a statistically significant increase in median PFS (p < 0.0069). (C) Time to progression is significantly higher in patients with a percentage of weight loss > 6.90% (p = 0.00898).