Figure 4.

Loss of sensory innervation alters adhesion molecule expression in the colon during Citrobacter rodentium infection. Expression of adhesion molecules (A) and chemokines (B) involved in the homing and migration of adaptive immune cells into the colonic mucosa were evaluated by quantitative polymerase chain reaction at 10 and 29 days postinfection (p.i.). Data are presented as mean ± standard error of the mean: *, P < .05, **, P < .01, and ***, P < .001 versus uninfected mice; #, P < .05 and ##, P < .01 compared with vehicle C rodentium-infected mice; one-way analysis of variance with Tukey posttest, with 8–12 animals per group.