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. 2020 Jan 23;221(12):2035–2042. doi: 10.1093/infdis/jiaa020

Table 1.

Samples Collected From the Patient and his Brother and Results of Phenotypic and Genotypic Testing for Resistance

Result of Phenotypic Resistance Testing, IC50
Sample Number Subject Site Collection Date Acyclovir Foscarnet Resistance Indicated by Genomic Analysis
1 Patient Face August, year 1 Acyclovir
2 Patient Right parietal scalp August, year 1 Acyclovir
3 Patient Right parietal scalp October, year 1 I R 101.6 Acyclovir
4 Patient Right parietal scalp November, year 1 R 10.6 S 75.0 Acyclovir
5 Patient Eye June, year 2 I I
6 Patient Scrotum August, year 2 Acyclovir, cidofovir
7 Patient Scrotum August, year 2 R 11.1 I
8 Patient Right parietal scalp July, year 3 R >64.0 I Acyclovir
9 Patient Left occipital scalp July, year 3 Acyclovir
10 Patient Lip February, year 4 S 1.7 S 33.0
11 Patient Lip March, year 4 Acyclovir
12 Patient Lip April, year 4 R 3.1 S 31.3
Brother Eye March, year 4 I S 12.9 Acyclovir

Abbreviations: I, indeterminant; IC50, half maximal effective concentration; S, sensitive; R, resistant.