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. 2020 May 26;9:e57410. doi: 10.7554/eLife.57410

Author response image 1. EKAR4 exhibits improved dynamic range over existing EKAR constructs.

Author response image 1.

A) Average line traces of EKAR responses to EGF in Hek-293T cells. B) Quantification of max amplitude responses from each respective EKAR. (**** p<0.0001 using one-way ordinary ANOVA, n=20 EKAR-EV and EKAR2G1, n=18 EKAR3.5, n=29 EKAR4.).