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. Author manuscript; available in PMC: 2021 Nov 1.
Published in final edited form as: Addict Biol. 2019 Dec 12;25(6):e12822. doi: 10.1111/adb.12822

Figure 1. Oral oxycodone self-administration: concentration-response curve.

Figure 1.

Data for each concentration represent the average of the last 3 days of self-administration. (A) Average active lever presses. (B) Average inactive lever presses. (C) Average reinforcers earned. (D) Average intake in mg/kg. (E) Average active lever presses for the last 3 days of re-introduced 0.1 mg/ml oxycodone compared to average of last 3 days of water. (F) Average inactive lever presses for the last 3 days of re-introduced 0.1 mg/ml oxycodone compared to average of last 3 days of water. Data expressed as mean values ± SEM. ##p<0.01, #p<0.05, compared to water. **p<0.01, compared to males. n=4–6/sex.