Table 2A.

Observed objective response rate (ORR) by tumor histology subtype

	N	ORR (%)	OR (95% CI) vs. PUC	p value
PUC	278	28%
VUC	117	29%	1.03 (0.64 - 1.66)	0.90
Squamous	50	28%	0.98 (0.50 - 1.91)	0.95
Micropapillary	25	28%	0.98 (0.39 - 2.44)	0.97
Sarcomatoid	16	38%	1.51 (0.53 – 4.30)	0.44
Plasmacytoid	12	17%	0.50 (0.11 - 2.35)	0.38
Adenocarcinoma	10	20%	0.63 (0.13 – 3.03)	0.56
NE	8	25%	0.84 (0.17 – 4.25)	0.83
			OR (95% CI) vs. VUC w/o NE
VUC without NE	109	29%
NE	8	25%	0.80 (0.15 – 4.19)	0.79

NE: neuroendocrine, PUC, pure urothelial carcinoma; VUC, variant urothelial carcinoma