Table 5. Univariate and Multivariate Cox Regression Analysis of Prognostic Factors for Lung-Related Mortality in Patients with COPD.

Variables	No.	Univariate Analysis		Multivariate Analysis
		HR (95% CI)	P	HR (95% CI)	P
Age (years)
> 70	81	3.746 (1.759–7.977)	0.001	2.961 (1.310–6.693)	0.009
≤ 70	241
Sex
Female	24	0.045 (0.000–51.809)	0.389
Male	298
BMI (kg/m2)
< 22.7	90	5.276 (2.467–11.282)	< 0.001
≥ 22.7	232
FEV1 (% predicted)
< 50	148	4.805 (1.946–11.862)	0.001	3.912 (1.485–10.309)	0.006
≥ 50	174
DLCO (% predicted)
< 51	80	7.023 (3.270–15.083)	< 0.001	2.551 (1.003–6.484)	0.049
≥ 51	242
EI (%)
> 34	80	8.585 (3.755–19.628)	< 0.001	2.408 (0.844–6.870)	0.100
0–34	242
Vertebral fracture
Presence	63	2.472 (1.118–5.467)	0.025
Absence	259
DThorax (HU)
< 119.3	142	5.491 (2.331–12.932)	< 0.001	4.345 (1.707–11.060)	0.002
≥ 119.3	180