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. 2020 Jun 12;55(9):877–887. doi: 10.1007/s00535-020-01693-9

Table 2.

Prognostic factors for overall survival identified by univariate and multivariate analyses (n = 100)

Variables n (%) Univariate Multivariate
p value HR 95% CI p value
Age
 <66 years 50 (50.0) 0.002 1 0.090
 ≥66 years 50 (50.0) 2.026 0.899–4.939
Sex
 Male 67 (67.0) 0.376
 Female 33 (33.0)
Procedure
 Sp + Dev 45 (45.0) 0.005 1 0.730
 BRTO 55 (55.0) 1.253 0.361–4.798
Serology of viral hepatitis
 HBV or HBC 55 (55.0) 0.732
 Non-B and non-C 45 (45.0)
Concurrent HCC
 Yes 44 (44.0) 0.289
 No 56 (56.0)
White blood cell counts
 ≥3240 (mm3) 57 (57.0) 1 0.642
 <3240 (mm3) 43 (43.0) 0.036 1.303 0.441–4.249
Hemoglobin
 ≥10.7 (g / dL) 57 (57.0) 1 0.945
 <10.7 (g / dL) 43 (43.0) 0.002 1.038 0.342–2.910
Platelet counts
 <6.6 (×104/mm3) 33 (33.0) 0.020 1 0.156
 ≥6.6 (×104/mm3) 67 (67.0) 2.438 0.726–9.737
Total bilirubin
 <0.8 (mg/dL) 79 (79.0) 0.100
 ≥0.8 (mg/dL) 21 (21.0)
Aspartate aminotransferase
 <43 (IU/L) 65 (65.0) 0.005 1 0.983
 ≥43 (IU/L) 35 (35.0) 1.010 0.417–2.544
Alanine aminotransferase
 <29 (IU/L) 57 (57.0) 0.091 1 0.101
 ≥29 (IU/L) 43 (43.0) 2.382 0.844–6.725
Albumin
 >3.6 (g/dL) 37 (37.0) 0.001 1 0.042
 ≤3.6 (g/dL) 63 (63.0) 4.099 1.049–19.036
Prothrombin time% activity
 >80 (%) 19 (19.0) 0.045 1 0.039
 ≤80 (%) 81 (81.0) 4.324 1.070–29.699
Creatinine
 <0.84 (mg/dL) 64 (64.0) 0.013 1
 ≥0.84 (mg/dL) 36 (36.0) 3.229 1.524–6.967 0.002

HR hazard ratio, CI confidential interval, HCC hepatocellular carcinoma, Sp + Dev splenectomy and gastric devascularization, BRTO balloon-occluded transvenous retrograde obliteration, HBV hepatitis B virus, HCV hepatitis C virus