Table 2.
Characteristics | Univariable, HR (95%CI) | p value | Multivariable*, HR (95%CI) | p value |
---|---|---|---|---|
Gender (Female vs Male) | 1.09 (0.69–1.72) | 0.70 | ||
Age | 1.07 (1.05–1.09) | <0.001 | 3.17 (1.84–5.44) | <0.001 |
Ethnicity, European vs other |
0.93(0.49–1.86) | 0.91 | ||
Body Mass Index | 0.96(0.90–1.02) | 0.25 | ||
Presence of comorbidity (vs none) | 3.91 (2.26–6.84) | <0.001 | ||
Hypertension | 2.60 (1.67–4.05) | <0.001 | ||
Diabetes | 1.51 (0.96–2.05) | 0.06 | ||
Coronary artery disease | 3.21 (2.02–5.10) | <0.001 | 2.93 (1.77–4.86) | <0.001 |
Chronic kidney failure | 2.75 (1.47–4.40) | <0.001 | ||
Cancer | 2.77 (1.47–5.22) | 0.002 | 2.32 (1.15–4.67) | 0.01 |
Radiographic assessment of lung edema score | 1.04 (1.02–1.06) | <0.001 | 1.05 (1.03–1.07) | <0.001 |
White blood cell count, x109/L, (median) | 1.71 (1.11–2.62) | 0.001 | ||
Lymphocyte count, x109/L, (median) | 2.24 (1.42–3.52) | <0.001 | 1.83 (1.14–2.95) | 0.01 |
Hemoglobin, g/dl, (median) | 0.52 (0.33–0.80) | 0.003 | ||
Platelets, x109/L, (median) | 0.89 (0.59–1.34) | 0.59 | ||
Glucose, mg/dl, (median) | 2.63 (1.62–4.28) | <0.001 | ||
ASpartate Transaminase, U/L, (median) | 1.28 (0.84–1.95) | 0.23 | ||
C-Reactive protein, mg/L, (median) | 1.53 (1.03–2.35) | 0.04 | ||
Lactate deydrogenase, U/L, (median) | 2.28 (1.32–3.94) | 0.003 | ||
D-Dimer, microgr/ml, (median) | 2.02 (1.03–3.96) | 0.03 | ||
Lactate, mmol/L, (median) | 2.00 (1.27–3.15) | <0.001 | ||
Creatin Kinase, U/L, (median) | 1.16 (0.72–1.88) | 0.52 | ||
Serum Ferritin, ng/ml, (median) | 0.88 (0.50–1.53) | 0.65 | ||
Procalcitonine, ng/ml, (median) | 2.09 (1.15–3.80) | 0.01 | ||
N-terminal prohormone of brain natriuretic peptide, pg/mL, (median) | 4.82 (2.43–9.54) | <0.001 |