Table 1.
Different types of human coronavirus (HCoVs).
Discovery | HCoV genera | Coronaviruses | Natural Host | Cellular receptor |
---|---|---|---|---|
1966 | α-CoV | HCoV-229E | Bats | Human aminopeptidase N (CD13) |
1967 | β-CoV | HCoV-OC43 | Cattle | 9-O-Acetylated sialic acid |
2003 | β-CoV | SARS-CoV | Palm Civets | ACE2 |
2004 | α-CoV | HCoV-NL63 | Palm Civets, Bats | ACE2 |
2005 | β-CoV | HCoV-HKU1 | Mice | 9-O-Acetylated sialic acid |
2012 | β-CoV | MERS-CoV | Bats, Camels | DPP4 |
2019 | β-CoV | SARS-CoV-2 | Bats, ? | ACE2 |