Table 1.
Immunological assessment per group previous polysaccharide vaccination
| NHL No: 17 | MGUS No: 13 | CLL No: 10 | |
|---|---|---|---|
| IgG (mg/dL) | 424±303 356 (530) |
1.360±793 1.131(1.106) |
553±358 344 (608) |
| IgA (mg/dL) | 48±61 18 (81) |
141±92 111 (146) |
96±155 22 (68) |
| IgM (mg/dL) | 42±45 25 (67) |
252±385 95 (169) |
29±31 12 (37) |
| IgG1 (mg/dL) | 268±223 194 (356) |
844±607 523 (732) |
280±150 240 (233) |
| IgG2 (mg/dL) | 130±100 95 (115) |
286±193 235 (235) |
228±197 118 (328) |
| %Neutrophils | 51±12 56 (12) |
49±18 51 (25) |
25±19 14 (45) |
| Neutrophils (cells/mm3) | 2,403±1.463 2,600 (2,100) |
2,057±1.341 3.050 (2.450) |
1,836±1.704 2,800 (2,400) |
| Lymphocytes (cells/mm3) | 1,611±931 1,400 (931) |
1,772±1,401 1,700 (1,500) |
11,800±16,881 4,900 (9,850) |
| %B lymphocytes | 7±6 6 (9) |
13±12 11 (9) |
49±35 45 (76) |
| CD19 B cell lymphocytes (cells/mm3) | 107±143 62 (152) |
142±82 145 (142) |
2,888±3,486 1,251 (5,235) |
| %CD4+ T-lymphocytes | 29±7 26 (11) |
42±12 44 (21) |
19±16 16 (31) |
| CD4+ T-lymphocytes (cells/mm3) | 464±295 434 (562) |
751±362 754 (496) |
837±437 574 (909) |
| %NK cells | 16±9 14 (17) |
12±6 11 (9) |
7±7 4 (9) |
| NK cells (cells/mm3) | 202±156 121 (252) |
207±132 146 (200) |
473±404 204 (755) |
Data are presented as mean±standard deviation; median (Interquantilic Range; IQR).
M-component in the MGUS group (%; g/dL and Kappa/Lambda ratio): 13.8±7.71; 15.3 (12.8%). 1.03±0.63; 1.09 (1.03 g/dL). 0.99±1.15; 1.02 (2).
Reference values: serum immunoglobulins (mg/dL) IgG: 767–1,590; IgA: 61–356; IgM 37–286.
Immunoglobulin subclasses (mg/dL) IgG1: 341–894; IgG2: 171–632.
Reference values for CD4+ T-lymphocytes: 51-66%; 464-1,721. CD8+ T-lymphocytes: 28-36%; 178-853. CD19 B lymphocytes: 7-13%; 92-515; NK cells CD3-CD56+CD16+: 8-19%; 82-594.