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. 2020 Jun 5;13:103. doi: 10.3389/fnmol.2020.00103

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Copyright © 2020 Si, Li, Ye, Li, Liu, Kuang, Chen and Zhu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The inverse relation between SG formation and apoptosis levels in PC12 cells and primary cortical neurons under OGD/R stimulation. (A) SG formation in primary cortical neurons treated with different times of reperfusion (0, 6, 12, 18, and 24 h) after 6 h of OGD stimulation. SG labeled with TIA1 (green), G3BP1 (red), and DAPI (blue). (B) SG formation in PC12 cells treated with different times of reperfusion (0, 6, 12, 18, and 24 h) after 6 h of OGD stimulation. (C) Apoptosis levels in PC12 cells treated with different times of reperfusion (0, 6, 12, 18, and 24 h) after 6 h of OGD stimulation. Scale bars: 10 μm. ****P value < 0.0001.