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. 2020 Jun 5;11:821. doi: 10.3389/fphar.2020.00821

Figure 2.

Figure 2

Berberine increased the tension of freshly isolated left ventricular muscle (LVM) strips. (A, B) Original isometric tension recordings showing that berberine (100 µM) increased the tension of LVM strips. (C) Summary data showing that berberine increased the tension of LVM strips in a concentration-dependent manner. The numbers of repeats are as follows: 30 µM Ber, n = 10, N = 10; 50 µM Ber, n = 7, N = 7; 100 µM and 300 µM Ber, n = 11, N = 11; 200 µM Ber, n = 12, N = 12; n and N are the numbers of LVM strips and rats, respectively. Ber stands for berberine. **p < 0.01, ***p < 0.001 vs. vehicle control group; two-way ANOVA with Sidak's multiple comparisons test.