Table 2.
OATP1B1 phenotypes | SLCO1B1 diplotypes | Phenotype frequencies (%) | ||||||
---|---|---|---|---|---|---|---|---|
Worldwidea | Total | Northern | Central | North eastern | Southern | Bangkok | ||
Normal function |
*1a/*1a
*1a/*1b *1b/*1b |
55 – 88 | 75.85 | 76.70 | 73.27 | 74.14 | 84.91 | 72.86 |
Intermediate function |
*1a/*5
*1a/*15 *1b/*5 *1b/*15 |
11 – 36 | 22.57 | 22.58 | 24.84 | 24.27 | 13.21 | 24.29 |
Low function |
*5/*5
*5/*15 *15/*15 |
0 – 6 | 1.58 | 0.72 | 1.89 | 1.58 | 1.89 | 2.86 |
a, Frequency of the polymorphism varies by ancestral group.