Table 4.
The Bayesian approach of AUC0–12h.
| Model | N | Time | r2 | PE range (%) | RMSE | ICC (95% Cl) | Limits of agreement (%) |
|---|---|---|---|---|---|---|---|
| 1 | 37 | C1h | 0.846 | −36.45 to 54.64 | 22.73 | 0.830 (0.686–0.912) | −21.67 to 26.72 |
| 2 | 37 | C0h | 0.862 | −41.27 to 45.76 | 21.85 | 0.914 (0.832–0.957) | −15.47 to 21.15 |
| 3 | 34 | C2h | 0.922 | −23.98 to 47.67 | 18.76 | 0.942 (0.887–0.971) | −12.01 to 15.29 |
| 4 | 37 | C4h | 0.976 | −14.57 to 31.33 | 12.80 | 0.985 (0.970–0.992) | −8.833 to 7.358 |
| 5 | 37 | C0h+C4h | 0.988 | −15.62 to 22.78 | 9.34 | 0.994 (0.988–0.997) | −5.801 to 4.638 |
| 6 | 34 | C0h+C2h | 0.984 | −16.30 to 19.23 | 9.81 | 0.991 (0.982–0.995) | −5.647 to 7.040 |
| 7 | 31 | C2h+C8h | 0.990 | −15.83 to 11.84 | 7.73 | 0.987 (0.934–0.996) | −3.443 to 8.322 |
| 8 | 33 | C1h+C4h+C8h | 0.996 | −10.48 to 6.36 | 4.68 | 0.996 (0.982–0.998) | −2.338 to 4.976 |
| 9 | 20 | C1.5h+C4h+C8h | 0.998 | −8.94 to 3.41 | 4.42 | 0.997 (0.971–0.999) | −1.763 to 5.154 |
| 10 | 20 | C1h+C1.5h+C4h+C8h | 0.998 | −5.46 to 2.85 | 3.26 | 0.998 (0.987–0.999) | −1.930 to 3.655 |
AUC0–12 h, the area under the concentration-time curve from 0 h to 12 h; PE, prediction error; RMSE, root mean square error; ICC, intraclass correlation coefficient.