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. 2020 Jun 5;14:203. doi: 10.3389/fnhum.2020.00203

Table 8.

Clusters for control covariate, age, and MMSE, interactions.

Voxels P-value Z-Values peak MNI coordinates Structures
X Y Z
Age
Semantic fluency
Y > O 772 0.000752 7.36 −46 −48 44 L Inferior parietal sulcus, anterior intra-parietal sulcus, superior parietal lobule, lateral occipital cx.
O > Y 468 0.0179 5.84 −64 −24 28 L Secondary somatosensory cx/parietal operculum, inferior parietal lobule, primary somatosensory cx BA 1 and 2, primary auditory cx.
Finger-tapping
Y > O 403 0.0352 4.22 12 −20 70 R Premotor cx BA 6, corticospinal tract, primary motor cx BA 4, primary somatosensory cx BA 3.
MMSE
Semantic fluency
Y > O 1718 2.98 e-7 5.10 −2 −52 66 LR Superior parietal lobule, primary somatosensory cx, primary motor cx; R occipital pole, lateral occipital cx.
O > Y 1592 7.15e-07 5.81 40 −58 −6 R Optic radiation, lateral occipital cx, temporal occipital fusiform cx, inferior temporal gyrus, callosal body.
538 0.00824 6.09 −48 −54 −2 L Superior longitudinal fasciculus, middle temporal gyrus.
Finger-tapping
O > Y 522 0.00892 3.69 46 28 22 R Middle frontal gyrus, Broca’s area BA 44 and BA 45, inferior frontal gyrus, superior longitudinal fasciculus, premotor cx BA6.
374 0.05 4.24 30 −80 2 R Lateral occipital cx, optic radiation, callosal body, inferior longitudinal fasciculus, inferior fronto-occipital fasciculus.

Y, young group; O, older group; Y > O, steeper interaction slope for the young group; O > Y, steeper interaction slope for the older adult group.