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. 2020 Jun 5;11:1017. doi: 10.3389/fimmu.2020.01017

Table 1.

Profile of the healthy control group and periodontitis patients.

Number in figure IgG level (FDC381) IgG level (SU63) Number of present teeth Bone loss (Schei value)
Healthy H1 −0.383 0.155 28 N.D.
H2 −0.322 −0.239 28 N.D.
H3 −0.557 −1.367 28 N.D.
H4 −0.152 0.425 28 N.D.
H5 −0.536 −1.307 28 N.D.
H6 −0.562 −1.201 28 N.D.
H7 (a1) −0.634 −1.446 28 N.D.
H8 (a2) −0.647 −1.365 28 N.D.
H9 −0.635 −1.321 28 N.D.
H10 (a3) −0.666 −1.445 28 N.D.
Periodontitis b1 5.450 10.180 N.A. N.A.
b2 7.550 5.070 N.A. N.A.
b3 13.320 5.850 N.A. N.A.
c1 1.800 0.060 N.A. N.A.
c2 15.110 9.080 N.A. N.A.
c3 13.360 5.520 N.A. N.A.
P1 1.093 0.054 17 77.06
P2 2.365 1.558 17 55.59
P3 0.000 −0.813 10 55.50
P4 1.211 −0.504 27 53.33
P5 1.912 0.269 28 51.79
P6 1.052 −0.202 24 47.50
P7 2.415 0.755 22 44.77
P8 37.587 11.373 18 43.06
P9 0.040 −0.179 18 42.22
P10 3.901 3.246 25 38.80
P11 0.647 1.137 29 11.03
P12 1.207 0.648 30 15.83
P13 2.474 0.603 29 16.90
P14 0.000 −0.521 27 17.04
P15 8.073 1.324 25 19.80
P16 2.270 0.814 16 20.00
P17 −0.147 0.510 28 20.54
P18 18.572 4.248 30 20.67
P19 0.095 −0.378 28 20.89
P20 1.657 −0.454 17 23.53

Serum samples were obtained from 10 healthy subjects without bone loss (five male and five females; mean ± standard deviation age, 34 ± 5 years) and 26 patients with periodontitis (11 males and 15 females; mean ± standard deviation age, 52 ± 12 years). Serum IgG levels against P. gingivalis FDC381 and SU63 were measured by enzyme linked immunosorbent assay. The extent of bone loss was measured by the methods of Schei. Schei indices were classified as: <25% represents mild bone loss and >35% represents severe bone loss.

IgG levels of healthy subjects were usually lower than 1. In addition, healthy subjects had 28 teeth and no bone loss was detected (shown as N.D.). Meanwhile, numbers of teeth and bone loss of periodontitis patients used for affinity column (b1-b3 and c1-c3) were not available (shown as N.A.).